FDA Approves Easier-To-Swallow Version of Baclofen for Treating Spasticity in MS | MyMSTeam

Connect with others who understand.

sign up Log in
Resources
About MyMSTeam
Powered By
MULTIPLE SCLEROSIS
NEWS

FDA Approves Easier-To-Swallow Version of Baclofen for Treating Spasticity in MS

Medically reviewed by Evelyn O. Berman, M.D.
Written by Kevin Cyr, M.D.
Posted on February 4, 2022

  • A new formulation of the drug baclofen, called Lyvispah, has been approved to treat spasticity in people with multiple sclerosis (MS).
  • Balcofen is a commonly prescribed muscle relaxant used to soothe muscles and reduce discomfort.
  • Lyvispah will be available in oral granule form, making it easier to take for people with MS who experience dysphagia, or difficulty swallowing.

The U.S. Food and Drug Administration (FDA) has approved a new version of the muscle relaxant baclofen for treating muscle spasticity related to multiple sclerosis. Called Lyvispah, the formulation comes in dissolvable strawberry-flavored granules, making the medication easier to swallow than traditional pills or capsules. This is important for some people who experience dysphagia, or difficulty swallowing, which is common for people living with MS.

Other formulations of baclofen are administered as tablets, or in some cases as an infusion through the spinal canal. The new formulation allows for more people with MS to have access to the drug to treat spasticity.

Muscle spasticity is a feeling of stiffness in the hands, arms, and legs that can cause unexpected muscle movements or spasms. Spasticity is common for those living with MS and may cause discomfort on a daily basis. Researchers have found that as many as 80 percent of people living with MS will experience spasticity. The symptom can have a significant impact on the quality of life and comfort of those living with MS, but treatments can help curb the effects of spasticity.

Baclofen is one of the most commonly used muscle relaxants used to soothe muscles and reduce discomfort. Lyvispah consists of specially made granules of baclofen that can be dissolved into a liquid and taken by mouth with water, soft foods, or through an enteral feeding tube.

The most common side effects of Lyvispah include:

  • Drowsiness
  • Dizziness
  • Weakness
  • Nausea
  • Headache
  • Insomnia
  • Constipation
  • Urinary frequency
  • Fatigue

Lyvispah, developed by Saol Therapeutics, will be available in 5-milligram, 10-milligram, and 20-milligram dosages when it enters the market later this year.

Posted on February 4, 2022
All updates must be accompanied by text or a picture.

Become a Subscriber

Get the latest news about multiple sclerosis sent to your inbox.

Evelyn O. Berman, M.D. is a neurology and pediatric specialist and treats disorders of the brain in children. Review provided by VeriMed Healthcare Network. Learn more about her here
Kevin Cyr, M.D. is a physician with a focus in cardiovascular disease and bioengineering. Learn more about him here

Recent Articles

If you have multiple sclerosis (MS) and want to switch treatments, you may need to wait for one d...

MS DMTs and Washout Periods: 8 Facts To Know

If you have multiple sclerosis (MS) and want to switch treatments, you may need to wait for one d...
Explore how others with multiple sclerosis experience shoulder pain and what they recommend to tr...

Shoulder Pain and MS: Members Describe Symptoms and Share Tips

Explore how others with multiple sclerosis experience shoulder pain and what they recommend to tr...
Read on to find out possible causes of neck, jaw, or collarbone pain, and how others with MS have...

MS and Pain in the Collarbone, Neck, and Jaw

Read on to find out possible causes of neck, jaw, or collarbone pain, and how others with MS have...
Part of the Relapsing MS Playbook seriesEnter Cell 2 Content Here...Enter Cell 3 Content Here...E...

MS and Cold Sensitivity: How Does Cold Affect MS Symptoms?

Part of the Relapsing MS Playbook seriesEnter Cell 2 Content Here...Enter Cell 3 Content Here...E...
Learn how to manage MS symptoms and prepare for your doctor appointments.

Relapsing MS Playbook

Learn how to manage MS symptoms and prepare for your doctor appointments.
Part of the Relapsing MS Playbook seriesEnter Cell 2 Content Here...Enter Cell 3 Content Here...E...

Your Relapsing MS Checklist: Custom Questions About Symptoms and Self-Care

Part of the Relapsing MS Playbook seriesEnter Cell 2 Content Here...Enter Cell 3 Content Here...E...
MS News
MS News

Thank you for subscribing!

Become a member to get even more:

sign up for free

close