Most people start with as high a dose as can be tolerated of Baclofen. Tizanadine may be used additionally. In a small number of cases, like mine, severe and pretty disabling spasticity occurs and a baclofen pump becomes an option. I'm just now after 15yrs. of pretty bad spasticity, am seeking all the info on getting a pump. This pump administers high doses of baclofen directly into the spine. Most doctors try all oral spasticity medications first.