I take it. My Neuro was skeptical that it would do any good, but he was willing to let me try it. I think it's made a difference in my mood and in my energy level. I've. Taken it for about 3 months now.

Low-dose naltrexone (LDN) has reduced both my pain and fatigue. I get 50mg naltrexone pills (way cheaper from "GETLDN247" ❤️, just Google it 😊), than get it compounded into 4.5mg doses. I've been doing this a few years with volumetric dosing. 50ml of distilled water with a 50mg tab of Naltrexone. Dose 3.5mg (3.5ml) with an oral syringe at night pre-bed. LDN is made a huge difference to me. I was at the point of giving up work but on LDN I’m able to keep working. Initially I had a few nights of disturbed sleep but now no side effects except the good ones!

I've been on it for about a year now. I take 4.5mg at bed and I've found that it nearly obliterates the spasticity that was part of my sleep time routine. And my neuro was willing the write the prescription even as she wanted me to try Rituximab. If you opt to go that route make sure to get it from a pharmacy that compounds it correctly - like Skip's in Boca Raton, FL.

Just out of curiosity why won't your Dr. prescribe it? Has your Doc found a cure?

That is a weak argument by your doc. The current sales rack of MS DMDs are 30-35% effective at best...Can't we as the consumer base of said DMDs make our own purchasing decisions?

I have been taking Ldn for almost 3 years and tried to stop it and after about a week I went back on it because of the pain and fatigue. It helps me sleep and lessens the pain. My new doctor doesn't prescribe it but my formal doctor did and the new one said if it is not broke don't fix it. I believe we have to fight for ourselves and what we want. I could understand if there was a risk factor but none that I'm aware of.