And I would also suggest lots of fluids.....made a huge difference...was very sick after my first full dose...for 2nd shot, I premedicated and drank lots of fluids...did same thing for third shot.

good luck, i just take a couple motrin before my injection and dont have any flu symptoms

i am going on my 4th injection, i was on avonex before and every other week injection is awsome. I have had some site redness that lasts a couple weeks but thats it

Plegridy another ms med" is a group on Facebook all about Plegridy

@A MyMSTeam Member thanks for the info. I'm going to be taking my 3 injection friday, so far so good. I do keep myself very hydrated, it does help.

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