Connect with others who understand.

sign up log in
Resources
About MyMSTeam

Connect with others who understand.

sign up log in
Resources
About MyMSTeam
Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Plegridy Injection Site Reactions

Plegridy Injection Site Reactions

I have recently began taking Plegridy injections. 3 injections and do my 4th this week. I haven't had any side effects so far but the injection site gets red and tender and takes a long time to fade (my first one 8 weeks ago isn't as red or tender but still there). I've tried heat & ice before and after but nothing changed. Any suggestions?

A MyMSTeam Member said:

I had the same reaction, and after getting no help from Plegridy or my Neuo, I decided to try something. It occurred to me that maybe I was allergic to the carrier fluid they are using, so I started taking an OTC allergy pill a hour before injecting the shot (I like Zyrtec). Here is how I set up & take my shots: I take a Zyrtec first thing, then 30 mins later I take the shot out and warm it to body temperature by putting the shot under my arm, then I inject. I haven't had any site reactions now for about 6 months.

posted over 6 years ago
A MyMSTeam Member said:

Suzette - do you take the Zyrtec for a few days, or just the one time?

posted about 7 years ago
A MyMSTeam Member said:

I warmed my Plegridy injection to body temperature and still had the same reaction. I didn't use Zyrtec I used the Benadryl. I'm will try the Zyrtec in the near future to see if it makes a difference or not.

posted over 6 years ago
A MyMSTeam Member said:

Yes, @A MyMSTeam Member, I was worried this was going to be a permanent thing for me. I had finally gotten away from taking shots EOD, and was upset that I would have to settle for having spots everywhere! I told my doctor I was going to look like a giraffe in a couple months! lol....so glad I found something that works, that was also simple to use.

Oh, and for @A MyMSTeam Member, I only use it prior to the shot, unless I am having other allergy issues.

posted about 7 years ago
A MyMSTeam Member said:

I started Plegidy in April 2015, and have had the same experience. It occurred to me this is similar to a histamine reaction, and since I take antihistamines at times throughout the year I decided to try taking a Zyrtec 2 hours prior to my injection, and it works wonderfully. I have done this three times now and do not have any red spots, swelling, hot spots, or pain. Oh, and a nurse suggested warming the shot to body temperature instead of room temperature, so now I put my shot under my arm for 5-0 mins before injecting. Hope this helps.

posted about 7 years ago
Already a Member? Log in