I've been on it for 2 years now. I have been doing injection of Betaseron and Rebif since 2000 so I know a lot about lipoatrophy. First I have always injected myself, I'm more comfortable with that. Every prescribe injection spots that we are supposed to use, for me are completely lipoatrophy. I asked my doctor and he told me I could inject in any soft tissue. That being said you should speak with your doctor first. If you have been on it a little over 2 years I wouldn't worry about it. As for side effects I do my shot right before bed and sleep through the effects.

@ash214 First.... Copaxone did wonders for me! I would suggest it to anyone. However, I self injected for 17 years no real problems... Over the past few years after injecting for so long(yes I injected properly) I had hardening of the tissue. Bad lipoatrophy now. I had to stop the shots because I had it so bad, (remember 17 years) that I had 2 very bad reactions leaving wounds. I went on Gilenya. I DO RECOMMEND COPAXONE. Just follow the directions and make sure you rotate sites.

I've only been on it for 7 months & have been told to make sure you rotate your injection sites, use heat prior to injection & cold after. Also do not massage site until 24 hrs later. There is an app on smart phones that is free & reminds you where you need to inject next. I do manual injection so I can slowly inject. The auto injector injects pretty fast.

MattGusick, I think that is a great way to get the blood circulation to the skin. Great idea.