I have been on Rebif for over 3 years. Good MRI's. It's really helping me. The Rebidose single use autoinjector is great too. It's a nice, quick, smooth injection. I still get flulike symptoms but they are mild. I was also on Avonex for almost 8 years. Had to switch to something stronger. The side effects with Avonex where more intense. If you drink a lot of water on the day of the shot and the next day, you barely have any side effects. I am happy with my therapy.

Ty very much all these answers were very helpful

I think it's too thick to give yourself! I have Tysabri infusions because I'm a chicken!

Take Tylenol or ibuprofen at night before your injection and it will help with the flu like symptoms. It's just my thinking but I've always thought the 3 times a week injection is more effective than weekly. Also the Rebif doesn't go into the muscle with a longer needle. It's given sc or sub-Q when is a small needle that goes through the skin into the layer of fat and it can be given in the abdomen, arms, legs and hips. Good luck.

Can't you just use a lower dose?