Amantadine was originally for Parkinson's for movement disorders & they found on Some people it gave increased energy or wakefulness.. I was put on provigil by a top Dr at Jefferson university in Philadelphia. Just info to take or leave.

I'm on it and it works great, not perfect but good enough to help me get through the day.

This is an interesting set of answers and shows how VARIABLE this weird disease can be. 13 years ago I was on the BBC being Mr Angry MS patient as NICE has banned Provigil from everybody except narcoleptics.....having bought some from Canada and started taking it my wife INFORMED me that UNLESS I stopped she would either KILL me or LEAVE me......So I stopped as it made me SOOOOOO ANGRY.

I have now been taking Amantadine (Symmetrel) for 10 years, and although it killed Wilsons wife in House it has made my life so much better....LOL

I use to be on Modafinil, but found I was grinding my teeth and clenching my jaw a lot, the were good for the fatigue, unlike the amatadine I'm on now, they just take the edge off the fatigue, the apple cidar vinegar and alien Vera juice also help ☺

They took me of provigil saying it was not for MS. I was put on amantadine but I'm not sure if it's doing anything. I have been on it for several years now, But do not wont to stop it in case my fatigue is made worse.