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Has anyone else taking Plegridy noticed that your injection sites stay discolored for long periods of time? I have noticed a huge difference based on where I do my injection; my thighs seem to react the worst to the injection- they stay discolored and itchy for anywhere between 6-8 weeks afterward. My abdomen injections stay red for 2-4 weeks, but no itching. However, my arms seem to have no reaction at all other than a couple days of redness.

I am also noticing that now that I've been on it… read more

March 8, 2017
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A MyMSTeam Member

Wahls

August 4, 2017
A MyMSTeam Member

I've been on @Plegridy for about 3 months, just started my 2nd round of injection sites. They have all turned red and itchy (about the size of a baseball). The reaction doesn't show up for about 5 days. Seems like they probably just start to look clear about the time they get injected again. Arms went the best for me, but I did them last so I don't know if the order matters at all. I usually do a cold compress right after injection, and Advil before.

March 28, 2017 (edited)
A MyMSTeam Member

@A MyMSTeam Member, @A MyMSTeam Member -

Thanks for your responses!

I took two Benadryl before my injection this week and I also did my injection in my right arm. This time, I have no redness. I'm not sure if it's because my arms don't react as my abdomen and my thighs do, or if the Benadryl helped. I will have to try the Benadryl when I do a thigh injection to see if it makes any difference.

March 16, 2017
A MyMSTeam Member

Yes!! I have the same issues. My arms are the worst, then my stomach then my legs. I tried icing the injection sites a couple times a day for a few days after I inject and I also take 20mcg of reactine in the morning. Maybe you could try that and see if it helps. I got a script from my dr because it's expensive for long term use :)

March 11, 2017
A MyMSTeam Member

I just have started taking this drug and have only had 3 injections and it seems like every side effect and yes my thighs are still red from the first injection a month ago don't see any difference just alot of bad issues doctor reccomend l stop injection wonder what's next confused 🤔🤔🤔

March 8, 2017

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