I've not tried Rebif (am only diagnosed a year myself) but I can tell you, as you know full well already being a nurse, that one persons perfect drug is another persons horror story. I was on plegridy which most tolerate quite well, but for me- it decimated my WBC count, now I'm on Copaxone with virtually no side effects, but it's not helping. You don't want to hear it- none of us do but it seems to me that at this point that the best advice is give it a go and see what happens. At this point we could count falling over as a side effect of not taking it, and that's a pretty lousy one too so why not give it a try. As for the diet idea..... preaching to the choir here. I had JUST re glutened my boys who, when young, had an odd wheat sensitivity but had out grown it. SO when folks said go GF I said "Bite me" I know exactly what that costs in time, money & taste. But I'm dying to wear acute pair of shoes again one day and I miss dancing out my frustrations in the living room so, there is a book I finally agreed to read (likely the same one you mentioned in your bio called "the MS recovery diet") which does lay out a pretty good line of reasoning, also the book "Undoctored". These together have at least given me a handle on how to figure out what might be triggers for me. my advice, get comfortable with a great snack and power thru the book with a pen underlining what's interesting and skipping what's not. And don't forget it's you whose got MS, not MS whose got you..... Keep in touch! Hugs.......