I, too, was on Copaxone for 20 years when an MRI showed it was no longer working. I was switched to Tecficera. My fatigue level is through the moon, but taking care of my 15-month-old granddaughter keeps me up and moving. I wish Tecfidera would help with my walking speed.

From my personal experience....I started on Copaxone. In the next year I gained 5-6 new lesions. The next year I spent on Rebif, and it made me feel horrible. Finally I switched to Tecfidera. 4 and 1/2 years later, MRIs have been stable. I still have issues from time to time, but feeling the best I have on Tec. We can only hope that our treatments help slow things down! Hope this helps a little!

I have been on Tecfodera. 4. A. Year. Don’t seem 2. B. Helping

I am on Tecfidera. I have had minimal side effects. Prior meds included Copaxone, Rebif and Tysabri. All were O.K. The key is to make sure that you don't get taken off one without being placed on another. I was taken off of Copaxone due to a site infection by a prior doctor who did not put me on anything else. 4 months later I had a exasperation and ended up in a nursing home for 3 months. I had full functions (walking too) prior to the incident and now I am wheelchair bound and only able to use my left arm.

I get MRI on Saturday to see if I need to switch as well.. Hoping I don't need to.. I really like @copaxone... I've had worse spasticity too but I've been dealing with this diagnosis for 30 years