I’ve used Copaxone for 17 years and have no internal side effects, have had only two mild attacks in 21 years (but everyone is different). Copaxone is even better now since only 3 times a week (use to be every day). You must rotate around (I don’t do my arms, but do both hips, thighs, and both sides of stomach) to help with your skin getting firm or dented/dimpled-in with some areas. Ice can help, nurse will advise you to avoid skin irritation. That is my only small issue, otherwise no problem. Needle is very short like 1/4 in. Goes into your fat, muscle types hurts more and have longer needles. I don’t even feel it sometimes, but sometimes I hit a sensitive spot and stings a few seconds. I administer it with an Autoject. Just load and push button and it does the rest. Tried Tecfedera and didn’t like my face getting warm and red (flushing) for 20 min. twice a day and it affected my legs/walking in cold weather. Felt like walking through mud on occasion. Does that for some people according to an online search. However, my brother does fine with it (takes twice a day), he does get the flushing though. Hope this helps!

I've finally found the med for my MS DMT. KESIMPTA. This one does lower the immune system, buy don't they all? It's an easy injection once a month . I'm feeling so much better already. Copaxone doesn't even work from what I experienced. It's way too weak and it's old news. There's a wonderful support system for folks who need that with KESIMPTA. 🥰

I'm awaiting to be cleared for Mavenclad. It's a newer DMT for MS. It's in pill form. And you only have to take it a very short time. I will have a coach with MS Lifeline. I am waiting for my neurologist to get the results back from the lab.

I was on Copaxone in 2012 my very first Ms med. I was allergic to the medication. All that training to have a nurse come out and teach me how to inject myself. I knew something was wrong the way I felt after giving myself about three injections. I didn't feel any better I felt faint and was itching and started to break out on my arms and legs. I called the doctor.I was told to stop using it immediately. So then I was put on Tecfiderma not to long after. The scans showed it didn't work for me either. So what im saying is somethings work for some but not for all. All MS people and diagnosis are different. But we are all here to help on your journey and the decision and outcome that follows be blessed.

Well with my experience with both I prefer Copaxone. First off it doesn’t hurt more over time (I see that you were concerned about that). It has the fewest side affects out of all the medications last time I checked and I had none, (except for injection site skin areas firming up some or dimpling/small indentations, but rotating around each area helps with that). I’ve been on it for 20 years. The needle is short and it goes into fat, the injections that have longer needles go into muscle. Big difference. Barely any discomfort. They have you rotate around the body to give your skin a break. I chose to never do my arms (hard to reach, you can get some dimpling over time and didn’t want that on my arms and I think it would be the most tender), so I did both thighs, both hips (make sure you find some fat like back around more towards your bottom) and both sides of abdomen. Every once in awhile it stings for a few seconds because I didn’t find the best spot (ice helps with that), but 85% of the time I don’t feel it at all or it is barely noticeable. I only use the autoject that you’re offered/given when you start. You load the syringe, aim (rest it on skin) and push a button. Done. They also have assistance programs from manufacturer to help with the Copays (doesn’t matter how much you make). I pay nothing out of pocket. Insurance takes care of the rest. 😉

Tecfidera: For my brother who also has MS this medication causes him flushing twice a day when he takes it. His face turns red/flushed for like 20 minutes. No other issues for him. I had some Flushing that eventually went away for me, my brother’s flushing never left him. Taking pills like Tecfidera is favorable but it does have some side affects. I went off of it after a month or so because when working the playground outside at a school, the cold MI weather didn’t work well with it for me. My legs became stiff and it was hard to walk in building (like moving through mud). I looked it up and for some people it can affect your leg muscles. Everyone is different though so good luck with your choice! 😉