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NAD

A MyMSTeam Member asked a question 💭
Laurel, MD

I have been reading about NAD and how it can help Multiple Sclerosis. Anybody tried the suppliment? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC26...

June 5, 2018
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A MyMSTeam Member

I wonder if nicotinic acid... Aka niacin

I have a bottle of niacinamide on my shelf at work... I'm not consistent at all with taking it. It's something you can purchase otc.
it's basically a precursor to niacin.

There are two forms of vitamin B3. One form is niacin, the other is niacinamide. Niacinamide is found in many foods including yeast, meat, fish, milk, eggs, green vegetables, beans, and cereal grains. Niacinamide is also found in many vitamin B complex supplements with other B vitamins. Niacinamide can also be formed in the body from dietary niacin.

Do not confuse niacinamide with niacin, inositol nicotinate, or tryptophan. See the separate listings for these topics. (chemistry)

Niacinamide is taken by mouth for preventing vitamin B3 deficiency and related conditions such as pellagra. It is also taken by mouth for schizophrenia, hallucinations due to drugs, Alzheimer's disease and age-related loss of thinking skills, chronic brain syndrome, muscle spasms, depression, motion sickness, alcohol dependence, blood vessel swelling caused by skin lesions, and fluid collection (edema). Niacinamide is also taken by mouth for treating diabetes and two skin conditions called bullous pemphigoid and granuloma annulare.

June 5, 2018 (edited)
A MyMSTeam Member

Thank you @A MyMSTeam Member and @A MyMSTeam Member for the wonderful information on NAD(short acronym) (nicotinamide adenine dinucleotide) NADH(long acronym)((Nicotinamide Adenine Dinucleotide Hydrate) Niacin (nicotinic acid) is converted to nicotinamide (niacinamide), which is converted in the body to NAD. When NAD+ picks up 2 hydrogen electrons it makes NADH. NADH has a special role generating ATP (energy) through the oxidation of food molecules. NADH is directly involved in the cellular immune defense system. Special white blood cells, called macrophages, are responsible for direct elimination of foreign bodies such as bacteria, viruses, and molds. If you consume niacin rich foods, there's probably no reason to take it in pill form, pill supplements don't replace proper sources of nutrients we need they are additional supports to what we consume in food sources. Potential problem is most rely on mass produced food sources from grocery stores instead of personal gardens. We, in the MS Family have MS as the common but, have some very unique system differences that should always be taken into consideration when making therapy and dietary choices. Best wishes Family

June 7, 2018 (edited)
A MyMSTeam Member

@A MyMSTeam Member I had trouble understanding the article you provided or maybe I didn’t read far enough into it, but the opening few paragraphs left me with that huh? feeling. So I had to find a basic article that describes what NAD is and what it does and I’m attaching a link so if anyone else had same difficulty understanding it might help them like it did me:

http://aboutnad.com/what-is-nad/

June 6, 2018
A MyMSTeam Member

Here is the best article that I had seen discussing NAD+, MS, and Myelin repair, so I tried it. I'm a certified member of the "We have PPMS, what have we got to lose" club.

Miraculously, mice were walking again.

https://www.nature.com/articles/ncomms6101

June 6, 2018
A MyMSTeam Member

No have not heard anything about it. Stay ms strong 💪

June 5, 2018

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