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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyMSTeam Member asked a question 💭
Marion, IA

My generic does not work as well as the real. Cymbalta was a life saver for me. Insurance only covers generic. Is there anything I can do.

August 26, 2018
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A MyMSTeam Member

Get with your doctor and have him or her make a case for the real Cymbalta and ask the Insurance to cover the real Cymbalta. Call the insurance company and tell them the issue and ask them what you need to do to get the actual Cymbalta.

August 26, 2018
A MyMSTeam Member

Have you Dr. write a letter stating just as you have said, the generic is not working as well and the brand name is medically necessary.

July 25, 2024
MyMSTeam

Here is detailed information about Cymbalta (Duloxetine) for Multiple Sclerosis based on the knowledge base:

Overview
- Cymbalta (Duloxetine) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class
- It is prescribed to treat depression associated with multiple sclerosis (MS), as well as Show Full Answer

Here is detailed information about Cymbalta (Duloxetine) for Multiple Sclerosis based on the knowledge base:

Overview
- Cymbalta (Duloxetine) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.
- It is prescribed to treat depression associated with multiple sclerosis (MS), as well as diabetic peripheral neuropathy, fibromyalgia, and chronic musculoskeletal pain.
- Cymbalta works by changing the balance of neurotransmitters in the brain.

How to Take It
- Cymbalta is taken once or twice daily.
- It comes in delayed-release capsule form.

Common Side Effects
- Nausea
- Dry mouth
- Drowsiness
- Constipation
- Decreased appetite
- Excessive sweating

Rare but Serious Side Effects
- Worsening depression and suicidal thoughts
- Liver toxicity
- Low or high blood pressure
- Serotonin syndrome
- Abnormal bleeding
- Severe skin reactions
- Mania
- Seizures
- Glaucoma
- Urinary retention

Additional Information
- Cymbalta can also help treat neuropathic (nerve-related) pain, which is common in MS.
- Some researchers think antidepressants like Cymbalta may provide neuroprotection in MS, although more studies are needed.
- It is important to have good communication with your doctor and regular meetings with a therapist when using antidepressants.

For more details, you can visit:
- [Cymbalta — RxList](https://www.rxlist.com/cymbalta-drug.htm)
- [Depression Treatment — National MS Society](https://www.nationalmssociety.org/Symptoms-Diag...)

This information is based on the knowledge base provided.

July 25, 2024
Hi, this is just a check-in, based on a phrase you mentioned. If you — or anyone else who sees this — is thinking about self-harm, we want to say that you are an important part of this community. No part of this is easy, but there is support that can help. Read more >
A MyMSTeam Member

Let your neurologist know and maybe no substitutions can be given. What’s the point of taking it if it’s not working for you right ??!!!!!!

August 27, 2018
A MyMSTeam Member

True. I take Cymbalta too but it is the generic kind I think.

August 26, 2018

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