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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Ocrevus And Cancer

Ocrevus And Cancer

I recently found out that the drug Ocrevus can cause cancer, mainly breadt cancer in women. Have anyone been diagnosed with cancer or was even told that this drug causes cancer? Im angry that i had to find out through social media and not by my doctor or the infusion center.

posted almost 3 years ago
A MyMSTeam Member said:

The potential increase in cancer risk while on Ocrevus is a real thing, although the risk is very small. During clinical trials "Breast cancer occurred in 6 of 781 females treated with OCREVUS and none of 668 females treated with REBIF or placebo" and this comes directly from the drug manufacturer:
https://www.gene.com/medical-professionals/medi...

However, there is some debate about whether the increased rates of breast cancer were just due to the population of people on the drug or from Ocrevus itself.

I don't think that Ocrevus necessarily causes cancer but that there might be a very small increased risk because Ocrevus is a true immunossupressant. Immunossuppressants in general can increase cancer risk because they reduce your body's ability to fight any potential bad cells. The risk is small but they don't know that much about Ocrevus and long term usage. I think its something to be aware of if not slightly concerned for people with a family history.
https://multiplesclerosisnewstoday.com/2018/03/...

edited, originally posted almost 3 years ago
A MyMSTeam Member said:

Yes, My neurologist sent me for a breast exam before starting Ocrevus. I guess with coming off the Zinbryta after it being recalled or whatever I was just like well oK, its always something 🤦🏾‍♀️

posted almost 3 years ago
A MyMSTeam Member said:

My neuro and i discussed and based on my moms history of cancer and the fact that i have dense breast tissue that had put me in a recheck situation a few times when having my mamogram he told me the risk if breast cancer and the family history, althoufh bot breast cancer her felt i wouod triple my risk and wouldnt tecommend this dmd for me.

posted almost 3 years ago
A MyMSTeam Member said:

I'm on ocrevus and I was given the literature. Yes it was in the list of pros and cons. Your doctor should have made sure you had all the tools necessary to fully understand. To me, that's a failure upon your doctor who failed to fully educate you. With any of the medications that are prescribed for MS, there will always be risks. I was on avonex for a while and it wasn't doing its job. Even so, I had to do a liver enzyme test frequently to ensure there was no liver damage. It's the risk we all take just to feel better in hopes that a cure will be found. Until then, all we can do is hope and pray for the best. The major downfall to ocrevus is that the last couple of weeks you start to feel the symptoms. The best part, "for me", is that since I've been on it, I've had NO new lesions. Each individual will have their own opinion. However, we are stronger together by educating one another. Much love and thanks to all for we are a family.

posted almost 3 years ago
A MyMSTeam Member said:

No I haven't heard about it, but I know that some of these medications have terrible side affects

posted almost 3 years ago
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