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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyMSTeam Member asked a question 💭
Plano, TX

Good morning friends! I'm starting my round of steroids today (5 days). The pharmacy sends me (5) 1g vials of methylprednisol powder - looks like the vial used for injection - and I mix it in a smoothie. I have used it this way a few times before and it works very well, but the taste is just the worst - like you have a mouth full of metal! Anyone have experience with this - any tricks out there to help the taste?
Thank you in advance for any suggestions - everyone have a great day!

Nikki

July 27, 2022
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Reactions
A MyMSTeam Member

Peppermint works but Werther's Delights work better.

July 27, 2022
A MyMSTeam Member

You need to have a compound chemist as they will crush and make meds up. A normal chemist will only sell you what they have in boxes. I'm lucky my chemist is a compound chemist

May 12, 2023
A MyMSTeam Member

Interesting. You say you done this more than once before? I've never heard of it, I've only had IV solumedrol(works great) and oral prednisone(useless) so I'm curious exactly how well it works for you?

July 29, 2022
A MyMSTeam Member

I have only used it to inject iv with normal saline for the last 18 yrs. Never heard of using it oral. It shouldn't be used that way to my knowledge. There are oral pills they can subscribe for you that are simedrol.. I have done those when I couldn't do IV

July 27, 2022
MyMSTeam

It seems like you might be referring to Methylprednisolone. Here is some detailed information based on the knowledge base:

Solu-Medrol (Methylprednisolone) for Multiple Sclerosis

Overview
- Solu-Medrol is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to reduce inflammation.
- It is Show Full Answer

It seems like you might be referring to Methylprednisolone. Here is some detailed information based on the knowledge base:

Solu-Medrol (Methylprednisolone) for Multiple Sclerosis

Overview:
- Solu-Medrol is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to reduce inflammation.
- It is also known by its drug name, methylprednisolone.
- Commonly prescribed for adults with relapsing multiple sclerosis (MS) during acute exacerbations.
- It can rapidly improve symptoms such as weakness, vision, and mobility issues, and shorten hospital stays.
- Solu-Medrol is not a cure for MS but helps decrease symptoms associated with inflammation during MS flare-ups.

Mechanism of Action:
- Solu-Medrol is a corticosteroid, a type of hormone that suppresses the immune system response.
- It works by reducing the numbers of B cells and T cells (types of white blood cells) and inhibiting genes that control the production of cytokines.
- B cells, T cells, and cytokines are immune system factors that contribute to the attack on the nervous system in acute exacerbations of relapsing MS.

Administration:
- Usually administered intravenously in high doses periodically over four days.
- It may be given during hospitalization or on an outpatient basis.
- Always follow your doctor’s instructions exactly when taking Solu-Medrol.

Side Effects:
- Common side effects include:
- Upset stomach
- Restlessness
- Sleep disturbances
- Headache
- Sweating
- New growth of hair on the face or body
- People taking Solu-Medrol or other corticosteroids are more susceptible to infection due to the immunosuppressive nature of the drug.
- Take extra precautions against infection such as frequent hand-washing.
- Avoid contact with anyone who is or has recently been sick.
- Notify your doctor immediately if you develop signs of illness such as fever, sore throat, or a cough.
- Do not obtain vaccinations with live or attenuated viruses while on Solu-Medrol, and avoid contact with people who have recently received the oral polio vaccine.
- Psychological side effects can include mood swings, aggression, agitation, or nervousness. Notify your doctor if these changes become intense or difficult to manage.
- Prolonged use can cause more serious symptoms such as:
- Swelling in the face or lower extremities
- Rapid weight gain
- Acne or other skin problems
- Changes in hair
- Joint pain
- Pronounced increase in thirst
- Unexplained bruising
- Changes in the menstrual cycle

For more information, you can visit the detailed page on Solu-Medrol at [MyMSTeam](https://www.mymsteam.com/treatments/solu-medrol).

If you have any more specific questions or need further details, please let me know!

July 16, 2024