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Yes, it is possible to have a flare-up of multiple sclerosis (MS) without new lesions appearing on an MRI. In MS, particularly in relapsing-remitting MS (RRMS), inflammation can sometimes occur without causing new lesions that are visible on MRI scans. This is why monitoring symptoms and maintaining regular communication Show Full Answer

Yes, it is possible to have a flare-up of multiple sclerosis (MS) without new lesions appearing on an MRI. In MS, particularly in relapsing-remitting MS (RRMS), inflammation can sometimes occur without causing new lesions that are visible on MRI scans. This is why monitoring symptoms and maintaining regular communication with your healthcare provider is crucial, even if MRI results do not show new lesions.

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