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Several treatment options are available for managing trigeminal neuralgia (TN) in people with MS. Common medications include carbamazepine (Tegretol), gabapentin (Neurontin), pregabalin (Lyrica), and baclofen. While these medications can be effective, they may cause side effects like drowsiness and affect movement skills Show Full Answer

Several treatment options are available for managing trigeminal neuralgia (TN) in people with MS. Common medications include carbamazepine (Tegretol), gabapentin (Neurontin), pregabalin (Lyrica), and baclofen. While these medications can be effective, they may cause side effects like drowsiness and affect movement skills. Surgical procedures are also available when medications aren't providing enough relief. Gamma knife radiation is one of the most common surgical treatments for people with MS who have TN. This procedure applies radiation directly to the trigeminal nerve. Another option is microvascular decompression surgery, where padding is placed between blood vessels and the nerve to relieve compression. One MyMSTeam member shared success using Tegretol, while another found relief with Trileptal but noted the pain returns quickly if medication is stopped. Some people have also found help using topical pain relievers. It's important to work closely with your healthcare team to find the most effective treatment approach that doesn't interfere with your MS management.

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