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A MyMSTeam Member asked a question 💭
Kansas City, MO

I am starting on baclofen 10 and they seem not to take the pain away i

May 4, 2025
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Baclofen is a commonly prescribed medication for MS-related spasticity and muscle spasms. It's important to note that only about 4% of oral baclofen actually reaches the spinal cord where it's needed, which may explain why you're not experiencing immediate pain relief at 10mg.

If oral baclofen isn't providing adequate Show Full Answer

Baclofen is a commonly prescribed medication for MS-related spasticity and muscle spasms. It's important to note that only about 4% of oral baclofen actually reaches the spinal cord where it's needed, which may explain why you're not experiencing immediate pain relief at 10mg.

If oral baclofen isn't providing adequate relief, there are several options to discuss with your healthcare provider. They may adjust your dosage, consider alternative oral medications like Zanaflex, or in cases of severe spasticity, explore the option of an intrathecal baclofen pump. Many MyMSTeam members have found success with intrathecal baclofen pumps when oral medications weren't effective. The pump delivers medication directly to the spinal cord, which can result in better symptom control with fewer side effects than oral medication. One member shared that after getting a baclofen pump, they "could stand up straight, have no pain, and feel like a normal person again."

Remember to work closely with your healthcare provider to find the right treatment approach, as medication effectiveness can vary from person to person.

May 4, 2025
A MyMSTeam Member

Ive been on baclofen since 2006 for spasticity. Its one of the most important meds i take. 20 mg. 2 or 3 times daily. If there were side effects, i don't remember. All i know is it keeps painful palsy like spasms away. Grateful for it. Need it to live. I take gabapentin, lyrica and cymbalta for pain. Good luck. Navigating medication never ends. I used to cry every week I filled my case for years until COVID-19 hit. Now I hoard my extra pills like a lunatic. Good times! 😂 Lol. I laugh, cry then laugh again. MS sucks but I only have one life❤️🙏🧡

May 14, 2025
A MyMSTeam Member

Please ask your Neurologist what meds will work well for your specific situation! Hugs! 🤗🎶🦋

May 7, 2025
A MyMSTeam Member

I was prescribed Baclofen early on. Not for pain, but for spasticity. Had no effect other than making me feel drunk and not in a good way. I now take Fampridine, and it helps with my walking

May 4, 2025
A MyMSTeam Member

I actually have a baclofen pump. Puts liquid baclofen directly into my spine. Baclofen is more fore spasms and stiffness, not really pain. I am at an extremely high dose

May 4, 2025

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