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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyMSTeam Member asked a question 💭

Newly diagnosed SPMS

June 14, 2025
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A MyMSTeam Member

Been on it for two years without an issue. The nice thing with Siponimod, you ramp up so no monitoring like was required for Gilenya. Good luck for you and hope it slows down your disability progression.

June 14, 2025
MyMSTeam

Siponimod (Mayzent) is an FDA-approved medication specifically designed to treat Secondary Progressive MS. Clinical trials have shown promising results, with the medication reducing the risk of worsening disability by 21% and decreasing relapse risk by 55%.

The medication works by preventing white blood cells from entering Show Full Answer

Siponimod (Mayzent) is an FDA-approved medication specifically designed to treat Secondary Progressive MS. Clinical trials have shown promising results, with the medication reducing the risk of worsening disability by 21% and decreasing relapse risk by 55%.

The medication works by preventing white blood cells from entering your central nervous system, which helps reduce inflammation and protects nerve cells from further damage. Common side effects you may experience include:
- Headaches
- Urinary tract infections
- Falls
- Common colds

It's important to take this medication exactly as prescribed by your healthcare provider. The medication is taken orally, and your neurologist will discuss specific dosing instructions and potential side effects during your consultation.

June 14, 2025

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