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A MyMSTeam Member asked a question 💭
Portland, OR
September 3, 2025
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A MyMSTeam Member

Primary i separate as it said it’s always progressive. Secondary comes after relapsing remitting goes to progressive hope this helps

September 3, 2025
MyMSTeam

Primary progressive MS (PPMS) and Secondary progressive MS (SPMS) are two distinct forms of MS that begin differently:

PPMS occurs first and is present from the initial diagnosis. It affects about 10-15% of people with MS and is characterized by steady disease progression from the start, with no relapses or remissions Show Full Answer

Primary progressive MS (PPMS) and Secondary progressive MS (SPMS) are two distinct forms of MS that begin differently:

PPMS occurs first and is present from the initial diagnosis. It affects about 10-15% of people with MS and is characterized by steady disease progression from the start, with no relapses or remissions. SPMS, on the other hand, only develops after someone has already had relapsing-remitting MS (RRMS). About 50% of people with RRMS transition to SPMS within 10 years, and 90% transition within 25 years. The average age when people transition to SPMS is around 40 years old. Recent research suggests these conditions may be more complex than previously thought. Scientists now recognize that active inflammation and disease progression can occur simultaneously rather than in strict sequential stages.

September 3, 2025

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