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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyMSTeam Member asked a question 💭
Tyler, TX
December 26, 2025
 · 
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A MyMSTeam Member

If you're on baclofen PLEASE talk to your doctor if you notice mood changes. The roid rage gets bad sometimes and can be harder to notice if you're mid flare up (personal experience)

December 27, 2025
A MyMSTeam Member

Stretching. Baclofen. Tizanadine and some people use other meds

December 26, 2025
MyMSTeam

What medications and therapies can help with spasticity?

It's great that yoga is helping you! Stretching is one of the best non-pharmaceutical approaches for spasticity. Here are other options to consider:

First-line medications
* Baclofen (Fleqsuvy, Lyvispah, Ozobax DS) - provides the neurotransmitter GABA that helps Show Full Answer

What medications and therapies can help with spasticity?

It's great that yoga is helping you! Stretching is one of the best non-pharmaceutical approaches for spasticity. Here are other options to consider:

First-line medications:
* Baclofen (Fleqsuvy, Lyvispah, Ozobax DS) - provides the neurotransmitter GABA that helps relax stiff muscles
* Gabapentin (Neurontin)

Second-line medications:
* Tizanidine (Zanaflex) - particularly helpful for spasms
* Dantrolene sodium

Third-line medications:
* Clonazepam (Klonopin)
* Diazepam (Valium)
* Pregabalin (Lyrica)

Other treatment options:
* Botox injections for focal spasticity (like in one hand or arm)
* Baclofen pump for severe, widespread spasticity
* Physical therapy and aquatic therapy
* Orthotic devices like braces or splints

Lifestyle approaches that may help:
* Daily stretching (5 minutes before leaving your bedroom)
* Staying hydrated (one glass of water with each meal and between meals)
* Regular movement and exercise
* Avoiding triggers like stress, constipation, full bladder, tight clothing, and overheating

Some MyMSTeam members also report success with medical cannabis/CBD, foam rollers, topical creams, magnesium supplements, and dietary changes. Always discuss these options with your doctor before trying them.

December 26, 2025

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