Connect with others who understand.

  •   Learn from expert-reviewed resources
  •   Real advice from people who’ve been there
  •   People who understand what you’re going through
Sign Up Log In
Powered By
Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyMSTeam Member asked a question 💭
edmonton, alberta, CANADA

I currently take 60 mg of baclofen daily, spaced out every four hours. It sometimes gives me a headache and fatigue. Ant advice on options? Thanks, and happy new year!

December 31, 2025
 · 
Reactions
MyMSTeam

What are some alternatives or adjustments to baclofen for managing MS muscle spasms?

Happy New Year! It's understandable that headaches and fatigue from baclofen can be frustrating. Here are some options to discuss with your healthcare provider:

Managing Your Current Baclofen:

If baclofen helps your spasms but causes Show Full Answer

What are some alternatives or adjustments to baclofen for managing MS muscle spasms?

Happy New Year! It's understandable that headaches and fatigue from baclofen can be frustrating. Here are some options to discuss with your healthcare provider:

Managing Your Current Baclofen:

If baclofen helps your spasms but causes side effects, your doctor might adjust your dosing schedule or timing. Some people find taking it at night helps with sleep-related spasms while reducing daytime fatigue.

Taking baclofen with food might help if you experience any nausea alongside your headaches.

Alternative Delivery Method:

An intrathecal baclofen pump might be worth discussing. This device delivers baclofen directly into the spinal fluid, using about 100 times less medication than oral doses. A MyMSTeam member shared: "I had a baclofen pump implanted, and now I can stand up straight, have no pain, and feel like a normal person again."

This approach may cause fewer side effects like drowsiness and headaches, though it does require surgery and comes with its own considerations like infection risk or pump malfunction. Physical Activity as a Complement:

Gentle exercise like water activities, yoga, or Pilates may help with spasticity and can actually reduce MS-related fatigue. While it might feel counterintuitive when you're tired, low-impact movement could boost your energy levels.

Important Safety Note:

Never stop baclofen suddenly without medical guidance, as this can cause serious withdrawal symptoms including increased stiffness, fever, confusion, or seizures. Your doctor can help you safely adjust or taper your dose if needed.

Your healthcare team can explore whether adjusting your current regimen, trying the pump, or adding complementary approaches might work better for you.

December 31, 2025
A MyMSTeam Member

Thank you all for caring and sharing in a positive way.

January 1
A MyMSTeam Member

I do exercises in a pool. It calms my muscles. Sometimes I dance.

December 31, 2025
A MyMSTeam Member

I'm not keen on beclofen tabs
Will ask the Doctor for other type like Robaxin

December 31, 2025
A MyMSTeam Member

None of the muscle relaxers work on me so far. Dr. Naseer said that MS
blocks the effects of chemicals or medicines for some patients some of
the time. Cyclobenzaprine, Tizanidine, & Baclofen are all useless for me.

December 31, 2025

Related Questions

View All
A MyMSTeam Member asked a question 💭
Kingsport, TN

A MyMSTeam Member asked a question 💭
Preston, UK