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A MyMSTeam Member asked a question 💭
Pittsburgh, PA
January 6
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A MyMSTeam Member

What rare cancer can be caused by certain DMT?

April 24
MyMSTeam

Are you looking for opinions on Kesimpta (ofatumumab)?

Kesimpta is a self-injected medication that works as a B-cell depleting therapy, similar to Ocrevus. It's considered a highly effective disease-modifying therapy (DMT) for MS.

Some people have reported experiencing "crap gap" symptoms with Kesimpta - this refers to Show Full Answer

Are you looking for opinions on Kesimpta (ofatumumab)?

Kesimpta is a self-injected medication that works as a B-cell depleting therapy, similar to Ocrevus. It's considered a highly effective disease-modifying therapy (DMT) for MS.

Some people have reported experiencing "crap gap" symptoms with Kesimpta - this refers to feeling worse or experiencing symptom flare-ups as the medication's effects wear off before the next dose. These symptoms might include feeling drained or like you're getting sick.

One advantage of Kesimpta is that it's self-administered at home rather than requiring infusion appointments. However, like other B-cell depleting therapies, it may affect your immune response to vaccines, potentially resulting in a smaller antibody response (though T-cell response remains robust).

The decision to use Kesimpta should involve discussing with your neurologist what you're comfortable with and what fits your lifestyle. The most effective medication is ultimately the one you're comfortable taking consistently.

Have you discussed Kesimpta with your doctor as a treatment option, or are you currently considering switching to it?

January 6

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A MyMSTeam Member asked a question 💭
Pittsburgh, PA

A MyMSTeam Member asked a question 💭