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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyMSTeam Member asked a question 💭
Saskatoon, SK
February 4
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A MyMSTeam Member

Lyrica works great for leg spasms restless leg and nerve pain

February 5
MyMSTeam

What would you like to know about gabapentin?

Gabapentin is a medication sometimes prescribed off-label to help manage MS symptoms like nerve pain, numbness, pins and needles, burning sensations, and muscle spasms. It was originally approved as an anti-seizure drug, but it works by calming overactive nerve signals, which Show Full Answer

What would you like to know about gabapentin?

Gabapentin is a medication sometimes prescribed off-label to help manage MS symptoms like nerve pain, numbness, pins and needles, burning sensations, and muscle spasms. It was originally approved as an anti-seizure drug, but it works by calming overactive nerve signals, which can help reduce painful muscle spasms and stiffness.

Research shows gabapentin can be effective for MS-related spasticity and muscle symptoms, especially at moderate doses. Studies found it significantly improved muscle stiffness and pain compared to placebo.

However, experiences vary among people with MS. Some MyMSTeam members report relief from painful muscle spasms, while others haven't felt much benefit. One member shared that gabapentin helps prevent painful muscle spasms but doesn't seem to help with numbness. Common side effects include:
- Extreme sleepiness or drowsiness
- Vision problems (blurry or double vision)
- Dizziness
- Nausea, vomiting, diarrhea, or constipation
- Memory difficulties
- Weight gain
- Swelling in feet, ankles, legs, hands, or arms

These side effects often improve as your body adjusts to the medication.

If you're considering gabapentin or have specific questions about it, talking with your neurologist can help determine if it's right for managing your MS symptoms.

February 4

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