Does gabapentin help with muscle tightness and spasticity in MS?
Yes, gabapentin can help with muscle tightness and spasticity in MS, though results vary from person to person.
Research shows that gabapentin significantly improved spasticity compared to a placebo in studies. It works by calming overactive nerve signals Show Full Answer
Does gabapentin help with muscle tightness and spasticity in MS?
Yes, gabapentin can help with muscle tightness and spasticity in MS, though results vary from person to person.
Research shows that gabapentin significantly improved spasticity compared to a placebo in studies. It works by calming overactive nerve signals, which may help reduce painful muscle spasms and stiffness. One small MS-specific clinical trial found benefits for participants taking a certain dose three times daily.
However, gabapentin isn't considered a traditional muscle relaxant like baclofen. It's often prescribed off-label for MS symptoms including muscle spasms, nerve pain, and numbness.
What MyMSTeam members say:
Experiences vary widely:
- One member shared: "I know for me, gabapentin prevents the painful muscle spasms"
- Another noted: "I've been on gabapentin long term. I have never felt any relief, but my neurologist says he has nothing else to offer me"
The dose for muscle spasms can vary, so it's important to take it exactly as prescribed by your doctor. If you're not getting relief or experiencing side effects, talk to your neurologist about adjusting your dose or trying other options like baclofen, tizanidine, or physical therapy.
March 29
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