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A MyMSTeam Member asked a question 💭
Columbia, MO
April 29
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Can Solumedrol (methylprednisolone) help progressive MS the way it does for relapsing-remitting MS? This is a really important question.

Solumedrol is typically used to shorten the duration of relapses in relapsing-remitting MS (RRMS) by reducing inflammation. However, progressive MS works differently — it involves ongoing Show Full Answer

Can Solumedrol (methylprednisolone) help progressive MS the way it does for relapsing-remitting MS? This is a really important question.

Solumedrol is typically used to shorten the duration of relapses in relapsing-remitting MS (RRMS) by reducing inflammation. However, progressive MS works differently — it involves ongoing nerve damage and progression that isn't always driven by the same kind of acute inflammation that causes relapses. In progressive MS, the disease course is less about flare-ups and more about steady worsening. Because of this, Solumedrol tends to be less effective for managing progressive MS overall.

The main FDA-approved treatment for primary progressive MS is currently Ocrevus (ocrelizumab). For active secondary progressive MS, some relapsing MS therapies may also be options.

The key takeaway here is that treatment for progressive MS is an evolving area, with researchers actively exploring new therapies. It's really worth having a detailed conversation with a neurologist about what options make the most sense for your specific situation.

April 29

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