What is the likelihood of staying asymptomatic with MS in older adults diagnosed late while on a DMT?
The answer depends on several factors, including the type of MS, how stable the disease has been, and age. Here's a quick breakdown: By MS type, for adults 70+ with stable disease:
- Secondary Progressive MS (SPMS): An Show Full Answer
What is the likelihood of staying asymptomatic with MS in older adults diagnosed late while on a DMT?
The answer depends on several factors, including the type of MS, how stable the disease has been, and age. Here's a quick breakdown: By MS type, for adults 70+ with stable disease:
- Secondary Progressive MS (SPMS): An 88% chance of no disease recurrence in the 1–2 years after stopping a DMT
- Relapsing-Remitting MS (RRMS): Only a 41% chance of no disease recurrence after stopping a DMT
These numbers are for people who *stopped* their DMT, so staying on one would likely offer even better protection. Staying on a DMT matters a lot. Research found that people who stuck with their DMT regimen were 12 times more likely to be alive over a 19-year study period compared to those who didn't. That's a pretty compelling reason to keep up with treatment. That said, as people age, the immune system naturally slows down, which can mean fewer relapses — but it also means recovering from any relapse that does occur becomes harder.
Key factors that improve the odds of staying stable include:
- Being older (55+)
- Having had no relapses or new MRI lesions for 4+ years
- Having SPMS rather than RRMS
- Continuing DMT as prescribed
Always work closely with a neurologist before making any changes to a treatment plan.
August 30
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