Acthar Gel (Repository corticotropin hormone) for Multiple Sclerosis | MyMSTeam

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Acthar Gel is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat conditions including multiple sclerosis, psoriasis, rheumatoid arthritis, and lupus. Acthar Gel is also referred to by its drug name, repository corticotropin injection.

Acthar Gel is a type of hormone, an adrenocorticotropic hormone (ACTH) analogue. Acthar Gel is believed to work by stimulating the body to produce corticosteroid hormones, thereby controlling inflammation.

How do I take it?
Acthar Gel is usually administered as a subcutaneous or intramuscular injection.

Acthar Gel comes in the form of a multi-dose vial.

Side effects
The FDA-approved label for Acthar Gel lists common side effects including injection site reaction, weakness conditions (including fatigue, malaise, asthenia and lethargy), fluid retention (including peripheral swelling), insomnia, headache, and increased blood glucose.

Rare but serious side effects listed for Acthar Gel can include decreased bone density, elevated blood pressure, adrenal insufficiency, Cushing’s syndrome, gastrointestinal bleeding or perforation, neurological issues including severe depression or psychosis, eye disorders such as glaucoma or cataracts, and increased risk of infection.

For more information about this treatment, visit:

Acthar — Mallinckrodt

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