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The Symmetrel brand name has been discontinued in the U.S. Generic alternatives may be available.

Overview

Symmetrel is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for treating Parkinson’s disease and some types of influenza. It has also demonstrated effectiveness in relieving fatigue in people who have all types of multiple sclerosis (MS). Symmetrel is also known by its drug name amantadine. Symmetrel is not suitable for use by people who are allergic to rimantadine or who have a certain type of glaucoma, an eye disease. Symmetrel is classified as an antiviral and anti-Parkinsonian drug. It is unknown how it acts to decrease fatigue in those with MS.

How do I take it?

Symmetrel is taken orally with food or milk twice a day, usually in the morning and at midday in order to avoid disrupting sleep. Avoid alcohol while taking Symmetrel. Always follow your doctor’s instructions exactly when taking Symmetrel.

Side effects

Common side effects of Symmetrel include nervousness, dry mouth or nose, sleep disturbance, dizziness, loss of balance, blurred vision and a blotchy rash on the legs. Rare but serious side effects of Symmetrel include suicidal thoughts or behavior, seizures, neuroleptic malignant syndrome, kidney and liver disease, and melanoma. Seek medical help immediately if you experience symptoms of an allergic reaction such as trouble breathing, severe dizziness, a rash, or itching or swelling of the face, tongue and throat.

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