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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyMSTeam Member asked a question 💭
Ringwood, NJ

Has anyone else had issues with Rebif? I was diagnosed 1/09 and started taking Rebif shortly after. The side effects have driven me to the point where I am missing injections and I just don't want to do it anymore. I get injection site reactions and I have to inject before bed. If I inject too early I get horrible flu like symptoms and spike 101 fevers. I do it at night so that I usually sleep through all that. Regardless of when I inject I always end up with a headache that feels like the… read more

August 23, 2013 (edited)
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A MyMSTeam Member

I soak in a warm tub bath. Tylenol then straight to bed. I use

August 24, 2013
A MyMSTeam Member

Ask about Tysabri too. I also experienced the fever, pain, and headaches after injecting Rebif. After almost a year I changed over and I love it so far (just going for my 13th infusion next week).

August 27, 2013
A MyMSTeam Member

I liked rebif and all the side effects for two years, Now I use Tecfidera had one or two tough weeks now it s ok , I just need to get used to MS

August 24, 2013
A MyMSTeam Member

Have you tried ibuprofen before your injection instead of excedrin? I've heard it is more effective against the side effects.

August 23, 2013
A MyMSTeam Member

Rebif was a problem for me too, it seems alot of people have had issues with that drug. I had injection site reactions, bruising and flu like symptoms and increased pain...ugh! I hated those injections, I used to take 4 advils every because of the pain I cried alot because of that torture. Now I'm on Gilenya and its working so well for me.

August 23, 2013

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