No one knows how Tecfidera works. I asked my neuro the same question, and he said it was fine to get the flu vaccine. I am NOT inspired by the guesswork of these disease modifying drugs.

How does it work?

In multiple sclerosis, the immune system mistakenly attacks the myelin sheath that surrounds nerve cells in the brain and spinal cord. The damage disrupts the way in which messages, or nerve impulses, are carried to and from the brain, leading to a variety of symptoms.

Dimethyl fumarate's mechanism of action is not fully understood, but laboratory studies suggest that it may work in two ways1:

reduces the inflammation caused when the immune system attacks myelin, resulting in less damage to myelin.
protects nerve cells from damage caused by chemicals released during the immune attack.

I'm not sure. I haven't started taking this new treatment yet but I do plan on getting 1. I saw my neurologist today and was told I will be contacted by someone within 7-10 days.

I was told by my neuro that I should get one.

I have had both shots and the booster shot. I take the generic Vumerity my insurance made me switch from the brand name Tecfidera.😀 I also got my Flu shot

Ask your Doctors. They are the best ones to talk to. Each person is different, and some meds work differently for each person. Stay safe and in contact with your Doctors.