I have two spinal lesions and too many sub cortical brain lesions to count. My neuro says brain lesions are less debilitating, because other parts of your brain can take over for the damage parts (plasticity). Evidently the spinal cord does not have that ability, so just one lesion can cause significant problems. My experience is that brain lesions cause invisible symptoms--depression, cognitive problems, speech problems, fatigue.

I have 3 lesions on Brain and none any where else. My Nero went off of the lesions and lumbar pucture for my ms dx.

I have kind of given up on this stuff but I really wonder about these docs I had problems at the start since I had broken my neck 15 years earlier and over 15 mris ms never came up but getting worse and about 15 more mris when found 6 lesions same now 6 I have gone though 8 noro s for the last 15 mris most mabe all mris a report is made by some one else in asking a lot of? to docs in witch there's a lot you can really piss a doc off.i wasn't die.gitnose buy mris and there some with none and some with a lot so you tell me. sorry I guess with ppms and getting worse I see so much wasted money, time and expectations

for the last six years I've had no new lesions and steadily going down hill primary m s after reading all these pages the more I think all nuroigess and specialist need to answer the same way or amit they cant. l looked up ms brain lessons its petty wild.

i know this is an old post, but this was exactly what i was about to ask - it appears i have a lot on my brain ("inumerable lesions" according to the mri results.. consistent with a 30 year MS battle). Just got the results of my first spine and neck mri - it looks like there's none here. how is that possible? thanks to this thread, i know i'm not alone. thanks