I took Effexor for about a year & then switched to generic Zoloft b/c I was still feeling really low. Getting off Effexor made me absolutely evil & every single thing bugged me! It was really tough for about 10 days, but it was around Christmas time, so I felt like a jerk for feeling so icky! I've been on Zoloft for the last 3 yrs or so; a low dose of 50mg. This past fall, I was really feeling down, so I asked for my Dr. to up the dosage, which he did, to 100 mg per day. It hasn't adversely affected me & I don't feel so down. This winter w/ all the snow, but mostly no sun, has been tough, but seeing my Spring bulbs peeking out tells me that warmer, sunnier weather is on the way! Good luck w/ whatever you choose! ~R

I’m so glad that we have this space. I have gained approximately 20 pounds and did realize that it was odd as I wasn’t eating more. Cymbalta must be the culprit. See my PCP in early March and we will reduce the 60 mg dose - titrating down until it is out of my system because the weight is causing problems with my spine and making me less mobil. Immobility or being sedentary is not good.

I've never have taken Effexor. I did take Cymbalta & it was NOT fun going off of it. I will be starting Wellbutrion 150mg 2 X a day on Thursday. I'm hopeful that I'll have some improvement! I've heard a lot of good things about Effexor, wishing you the best!

I call my Effexor my Mood Stabilizer! If it's going to be a crazy, hectic day, I'll take my Rx of Effexor, then if needed, I'll take one about 4 or 5 hour's later. It kind of mellows me out.