Been on it for two weeks. I had some flushing the first two days, but that's it. No GI problems.

Flushing and diahhrea both ended after about 6 weeks.

I am on Tecfidera which is the latest oral that has been approved. I have had minimal side effects. Prior meds included Copaxone, Rebif and Tysabri. All were O.K. The key is to make sure that you don't get taken off one without being placed on another. I was taken off of Copaxone due to a site infection by a prior doctor who did not put me on anything else. 4 months later I had a exasperation and ended up in a nursing home for 3 months. I had full functions (walking too) prior to the incident and now I am wheelchair bound and only able to use my left arm.

I have been lucky with Tecfidera. I have had flushing (went away quickly) only three times since I started Tec three months ago. No GI trouble. I always take Tec with food. I think that helps.

how are you now on that drug?