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A MyMSTeam Member asked a question 💭
Cincinnati, OH

So my most recent MRI showed active and non active lesions. My neuro said he was more concerned with the non-active lesions on my brain. So much so, that he is putting me on steroids and Tysabri after only being on Gilenya for 3 months. He said it can't wait. He explained it, but he just spews information and I can't always grasp all the intelligence coming out of his mouth. lol. He just said that it was showing to be aggressive in a nutshell. I tried researching, but I am not finding too much… read more

January 19, 2016 (edited)
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A MyMSTeam Member

I second what @A MyMSTeam Member said. That's exactly what I was thinking, so thanks for saving me the typing!
@A MyMSTeam Member boots - essentially yes. When you have a CT, you have one with contrast and without typically. On the MRI, active lesions get brighter after the contrast has been administered. These are considered enhancing. An "enhancing" or active lesion is doing damage now. It's "turned on" I guess you could say? You may or may not have symptoms related to it. Steroids may or may not help to shorten the period of time that it remains active. Once it is done "doing its thing", it becomes inactive, or non enhancing, but it will always be there. Showing up on MRI.

January 19, 2016
A MyMSTeam Member

Yes, my neuro broke it down for me early on and said "it's kind of like real estate. It's all about location, location, location". We could have a bunch of lesions and they're not in an area that affects us or there could be just 1 that's in a 'not so great spot'. However, i'm not sure that applies here. Not sure how a nonactive lesion could be showing signs of aggression and I'm interested to learn more. It sounds like your neuro is thorough though which is good and being proactive...and i agree with the other responses, I would email him or jot down all of the questions you have and make sure you have him break it down for you at your next appt. It's also helpful to have another person with you who can help take it all in (including taking notes or even recording it if the doc doesn't mind) and digest with you later. Best of luck fellow warrior. Keep us posted.

January 19, 2016
A MyMSTeam Member

Wow, I would like to know that also! Is a non active lesions what they call non-enhancing? I had a few of both when I was diagnosed in Nov 2015 and I am tring to make sense of it all. Do you have the ability to send an email to your doctor? I would craft an email with your questions that you still have or new ones that arose after the appointment. Hopefully he is like my neurologist and will see the value in responding to you. It seems you never have enough time to ask all the questions you have, but my neurologist encouraged me to email her in between visits with any questions.

I would love to know the answers to your question on the non-active lesion.

Good luck, hugs to you!

January 19, 2016
A MyMSTeam Member

Active lesions are currently attacking, doing damage-Inactive lesions are scars which have already done their thing and have settled down. A lesion is just that- a scar. The body attacks the myelin sheath of the nerve (covering). What is left is a white scar on the brain or nerve, which shows up with your MRI. Glowing- bad. .....old scar, small white marking.

Read more: http://www.healthboards.com/boards/multiple-scl...

So maybe you should ask him in depth what is so concerning in your case to the Inactive lesions.

January 20, 2016
A MyMSTeam Member

Thank you all. I will come back to you with any answers I get! @A MyMSTeam Member I'm thinking you might be right. He showed me my new MRIs and I had a bunch of old and new lesions. My MRI in July only had 2.

January 19, 2016

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