I have not heard of such interaction, but maybe you are having an episodic interference with dietary add-ons like stevia. It isn't the copaxone so much as it may be how your body is processing the stevia. Since the headaches are an entirely unconnected occurrences, I would probably find another type of sweetener and see if you still have issues. Migraines are vaso-oriented, meaning dilation or constriction (opening or narrowing) the blood vessels; there's no correlation. I'm sorry you are having this difficulty. Perhaps talk to your Neuro or see if a consult with a registered dietitian is in order. Just suggestions. We're all different, as you know. I hope it gets better for you soon. 😊

There is no chemical reaction between Stevia and Copaxone. Copaxone is probably one of the safest drugs you can take for MS. I took it for a years. I did a ton of research on the product, how it was developed and was a patient speaker for that company years ago. Very safe drug, however, anyone can have a reaction to any drug or food. If it isn't working for you talk with your doctor, there are tons of other options now that were not available when I was on it. Good luck!

If you must have sugar try a local honey. I do not do any kind of sugar. I stopped getting migranes when I cut out the sugar and the drugs.

Addiotionally to what @A MyMSTeam Member posted headaches is listed as one of the common symptoms of @@ Copaxone.

Been told by my neuro that sweeteners of any type cause inflammation in the body which isn't good for any one living with MS.

Lakanto monfuit sugar-1:1 and ALL NATURAL, no chemically or off taste.

I just dbl checked, it is Monkfruit and ethyritol(safe for pups unlike xylitol which is deadly to pets)