@ChrisCristineChrissy Hi, I have the JCV virus & I was on Tysabri for over 2 yrs. My Dr took me off of it due to high risk of PML. He wanted me to go in Ocrevus but I opted out of meds all together. I'm on the Wahls Paleo plus diet. I've lost 60 lbs in 4 months , my symptoms are improving , and I'm feeling better overall.

I read a little article on Progressive multifocal leukoencephalopathy, PML is caused by an infection called
John Cunningham virus; JCV, there are two article sites : https://medlineplus.gov/ency/article/000674.htm and http://www.healthline.com/health/plm-virus#causes2
Who is at risk of developing PML?
PML is rare in people who have a healthy immune system. It is known as an opportunistic infection because it takes advantage of an immune system already compromised by illness. You’re at increased risk of developing PML if you:

have HIV-AIDS
have leukemia, Hodgkin’s disease, lymphoma, or other cancers
are on long-term corticosteroid or immunosuppressive therapy due to an organ transplant
You also have a slight risk if you have an autoimmune condition such as multiple sclerosis (MS), rheumatoid arthritis, Crohn’s disease, or systemic lupus erythematosis. This risk is higher if your treatment plan includes a drug that suppresses part of the immune system, known as an immunomodulator.

Learn more: The JC virus and risks for MS patients »

PML is a potential side effect of some disease-modifying drugs used to treat MS, including:

dimethyl fumarate (Tecfidera)
fingolimod (Gilenya)
natalizumab (Tysabri)
The longer you take these medications, the higher the risk of developing PML.

@A MyMSTeam Member I have been on TYSABRI for two and half years and my JCV numbers are elevating Right now I'm going through a three month wash out of the TYSABRI and the plan is to go Ocrevus. They are going to an M R I to check for PML activity before I start. Not sure what I would like for them to find. Getting tired of this MS and Trygeminal Neuralgia. At least PML would be a cure all. Oh well probably not what you were looking for. Hope all have a great up coming weekend.

Mentioned Users

A MyMSTea...

Has anyone found a job to do from home? I'd love to hear about it :)

Hi ChrisChtistineChrissy I was on Tysabri for may be six years and my doctor took me off Tysabri when she saw in my MRI some danger of me getting this deadly PML virus.
I try to follow Terry Wahls Paleo diet protocol but since I am a vegetarian it is difficult.