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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Has anyone with PPMS tried Ocrevus and if so how has it helped?

A MyMSTeam Member asked a question 💭
Cookeville, TN
February 14, 2020
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A MyMSTeam Member

There are a couple of closed groups on Facebook for Ocrevus that are probably the best source for information on this drug.
In a nutshell, like everything else MS related, it's not for everyone, especially if you are diagnosed as PPMS.

Here are two very good Ocrevus groups on Facebook to join....

https://www.facebook.com/groups/860023917470405/

https://www.facebook.com/groups/438394603178145/

And here is a group specifically for Ocrevus and Progressive MS....

https://www.facebook.com/groups/152024362299714/

February 15, 2020 (edited)
A MyMSTeam Member

Hi Judy,
I have had two full treatments of Ocrevus so I've been on it for a year. It has certainly helped with the numbness /weakness in my legs and I have better balance. I have noticed that it doesn't last the whole 6 months between treatments though.

February 14, 2020
MyMSTeam

Yes, people with Primary Progressive Multiple Sclerosis (PPMS) have tried Ocrevus (ocrelizumab). Here are some key points from the knowledge base:

- Mechanism: Ocrevus works by depleting B cells, which can contribute to PPMS by secreting destructive autoantibodies or activating other immune cells to attack the central Show Full Answer

Yes, people with Primary Progressive Multiple Sclerosis (PPMS) have tried Ocrevus (ocrelizumab). Here are some key points from the knowledge base:

- Mechanism: Ocrevus works by depleting B cells, which can contribute to PPMS by secreting destructive autoantibodies or activating other immune cells to attack the central nervous system.
- Efficacy: It has been shown to reduce the progression of clinical disability in individuals with PPMS.
- Progression Delay: People receiving Ocrevus were able to delay their progression to a wheelchair by an average of seven years, extending the time to 19.2 years without a wheelchair.

For more detailed information, you can refer to the resources provided in the knowledge base.

July 22, 2024
A MyMSTeam Member

I have PPMS and have been on ocrevus since 2017 diagnosed in 201 6.
I have not gotten any new brain lesions since starting ocrevus

December 6, 2022
A MyMSTeam Member

It has been prescribed now, frustrating period I'm in now is the insurance approval, I'll let you know once I have started.

August 28, 2022

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