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Mavenclad (Cladribine) for Multiple Sclerosis

Overview
- Drug Name: Cladribine
- Brand Name: Mavenclad
- Class: Immunomodulator, Purine Antimetabolite
- Approved By: U.S. Food and Drug Administration (FDA)
- Indications:
- Relapsing forms of multiple sclerosis (MS)
- Relapsing-remitting MS
- Active secondary Show Full Answer

Mavenclad (Cladribine) for Multiple Sclerosis

Overview:
- Drug Name: Cladribine
- Brand Name: Mavenclad
- Class: Immunomodulator, Purine Antimetabolite
- Approved By: U.S. Food and Drug Administration (FDA)
- Indications:
- Relapsing forms of multiple sclerosis (MS)
- Relapsing-remitting MS
- Active secondary progressive MS
- Usage: Typically prescribed when other treatments are ineffective or poorly tolerated.

Mechanism of Action:
- Function: Modulates the immune system.
- Action: Reduces the number of B and T lymphocytes, which are immune cells contributing to autoimmune attacks in MS.
- Additional Mechanism: Interferes with DNA processes in cells to prevent specific immune cells from replicating, helping control inflammation that damages nerve fibers.

Administration:
- Form: Oral tablet
- Dosage Schedule:
- Two separate treatment courses each year.
- Each course lasts two weeks.
- Approximately one month between the two treatment courses.

Side Effects:
- Common Side Effects:
- Headache
- Low white blood cell count
- Upper respiratory tract infection
- Rare but Serious Side Effects:
- Increased risk for low blood cell counts
- Serious infections
- Blood disorders
- Liver toxicity or injury
- Risk of developing graft-versus-host disease (GVHD) after receiving blood transfusions (GVHD is a severe immune reaction that can be fatal).

Additional Information:
- Resources: For more details, visit the official Mavenclad website: [Mavenclad — EMD Serono](https://www.mavenclad.com)

Community Support:
- MyMSTeam: A social network for people with multiple sclerosis and their loved ones, where members can share experiences and support each other.

References:
- Secondary-Progressive Multiple Sclerosis — Cedars Sinai
- How is Secondary MS Diagnosed — My-MS.org
- Secondary Progressive MS — National Multiple Sclerosis Society

For more information, you can visit the detailed page on Mavenclad at MyMSTeam: [Mavenclad (Cladribine) for Multiple Sclerosis | MyMSTeam](https://www.mymsteam.com/treatments/mavenclad).

 This AI-generated response comes from MyMSTeam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.

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