Linda was on Gilenya, but fell a few times so it was decided it wasn't working so she stopped. She had the same issue with tecfidera.

I have lived with my MS for 22 years, I took Avonex for 7 and Copaxone for 7 then switched to Ocrevus, the clinical evidence for Ocrevus is outstanding and I have done very very well on it. Kesimpta is similar, a little less data on the drug. I prefer Ocrevus because I only take it every 6 or 7 months, yes it’s an infusion but I was over taking shots. I also highly recommend everyone see a MS Specialist, not just a general neurologist, even if it is just once a year as they know so much more about the disease.

I switched from gilenya to kesimpta last year. I was on gilenya for 5 years. I feel better off of it, other tgan my legs.

I was on Gilenya for 3 years until 2018 when I had a heart attack, been on Tecfidera since.
Gilenya increases your heart rate by about 10 beats a minute, my lifestyle was more responsible for having the heart attack but I was told by back then that the latest research showed that Gilenya had more of an impact on the heart than previously thought.
The tecfidera seems to be working for me but tbh it's all a who knows kind of scenario with all these meds.

I am on Gilenya currently and am curious as well as my liver enzymes have been high while being on this and doc said we may look at switching