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A MyMSTeam Member asked a question 💭
williamsville, NY

PPMS

January 20, 2024
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MyMSTeam

Yes, several people and research groups have looked into stem cell therapy for multiple sclerosis (MS). Here are some key points from the knowledge base:

- Clinical Trials: A research group in Israel conducted a clinical trial with mesenchymal stem cells in participants with progressive MS. The results were positive Show Full Answer

Yes, several people and research groups have looked into stem cell therapy for multiple sclerosis (MS). Here are some key points from the knowledge base:

- Clinical Trials: A research group in Israel conducted a clinical trial with mesenchymal stem cells in participants with progressive MS. The results were positive, showing fewer participants in the treatment group experienced worsening symptoms compared to the placebo group.

- Personal Experiences:
- One MyMSTeam member reported significant improvements in muscle building and balance after treatment with umbilical cord cells in the Cayman Islands.
- Another member shared that their fatigue lessened for about two months after a stem cell transplant using fat cells.
- A different member reported no new or enhancing lesions six years after a stem cell transplant and has not needed disease-modifying drugs since.

- Research Findings:
- A small study suggested that autologous hematopoietic stem cell therapy (AHSCT) might be effective for severe relapsing-remitting MS (RRMS) and some cases of secondary progressive MS (SPMS), with 42% of participants showing no signs of progression five years post-transplant.

- Challenges and Risks:
- Stem cell therapy is still in early experimental phases and not widely available.
- Treatments can be costly and may not be covered by insurance as they are often considered experimental.
- There are potential risks, including the need for immunosuppressive drugs to prevent transplant rejection, which can lead to other health issues.

- Regulatory Status:
- The U.S. Food and Drug Administration (FDA) has approved the medications and procedures used in hematopoietic stem cell transplantation (HSCT) but not specifically for treating MS.

For more detailed personal experiences and research findings, you can refer to the MyMSTeam resources.

July 18, 2024
A MyMSTeam Member

My wife was diagnosed this past July with PPMS. She has had her first 2 half Ocrevus infusions in September and has her next full infusion the end of February. So far she seems to be getting a little worse but still fully mobile. Right leg numbness, needs to pee at least every hour. I am hoping her MRI's next month come back good. I am leery of stem cells as you need to go out of the country to get them. At this point the cost is not an issue.

January 20, 2024
A MyMSTeam Member

No not yet but hearing good things from some that hav

January 20, 2024

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