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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyMSTeam Member asked a question 💭
NC
August 31, 2025
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A MyMSTeam Member

I am on it At first I had some diarrhea but after about a week I just flush mainly on my head but sometimes my whole body

August 31, 2025
MyMSTeam

Many MyMSTeam members report experiencing flushing (temporary skin redness) and gastrointestinal symptoms like diarrhea, nausea, and stomach pain when taking Tecfidera. For most people, these side effects are mild to moderate and decrease after the first month of treatment.

To help manage flushing, members suggest
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Many MyMSTeam members report experiencing flushing (temporary skin redness) and gastrointestinal symptoms like diarrhea, nausea, and stomach pain when taking Tecfidera. For most people, these side effects are mild to moderate and decrease after the first month of treatment.

To help manage flushing, members suggest:
• Taking aspirin 30-60 minutes before Tecfidera
• Eating foods high in healthy fats (like peanut butter or avocado) before taking the medication
• Taking Tecfidera with food
• Avoiding alcohol Healthcare providers often recommend a slower titration schedule to reduce side effects:
• Weeks 1-2: 120mg once daily
• Weeks 3-4: 240mg once daily
• Week 5+: 240mg twice daily

It's important to space doses at least 8 hours apart and always take with food containing healthy fats like:
• Avocados
• Nuts and seeds
• Olive oil
• Fish

August 31, 2025
A MyMSTeam Member

Just flushing for a few weeks. Ive been on it since 2017

September 1, 2025

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