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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
September 8, 2025
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MyMSTeam

Baclofen is a commonly prescribed muscle relaxant that helps manage spasticity in MS by calming nerves in the spinal cord, which reduces both the frequency and intensity of muscle spasms. Many MyMSTeam members have shared their experiences with baclofen, with some reporting significant benefits.

While some members find Show Full Answer

Baclofen is a commonly prescribed muscle relaxant that helps manage spasticity in MS by calming nerves in the spinal cord, which reduces both the frequency and intensity of muscle spasms. Many MyMSTeam members have shared their experiences with baclofen, with some reporting significant benefits.

While some members find great relief with baclofen, others may not see much difference. This variation in response is normal, as everyone's experience with MS medications can be different. It's important to be aware of potential side effects, which can include:
• Drowsiness
• Sleep problems
• Muscle weakness
• Dizziness

For those with severe spasticity who don't get enough relief from oral baclofen, there's also an option called intrathecal baclofen therapy (ITB pump). One MyMSTeam member shared, "I had a baclofen pump implanted, and now I can stand up straight, have no pain, and feel like a normal person again."

September 8, 2025
A MyMSTeam Member

Thank you for replying. I hope you continue to have good results. For now, my husband has chosen Botox injections rather than taking Baclofen. It has lessened his pain, but the trade-off is that his weakness has increased.

December 31, 2025
A MyMSTeam Member

I started on a reduced dose of Baclofen because I still work and drive during the day. It has brought relief to my leg pain and and throat spasticity.

December 30, 2025

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