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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
September 27, 2025
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A relapse (also called a flare-up or exacerbation) occurs when you experience new symptoms or worsening of existing symptoms that last for at least 24 hours. Relapses typically develop over 24-48 hours and reach peak severity within several days.

Common symptoms to watch for during a relapse include
• Numbness or tingling Show Full Answer

A relapse (also called a flare-up or exacerbation) occurs when you experience new symptoms or worsening of existing symptoms that last for at least 24 hours. Relapses typically develop over 24-48 hours and reach peak severity within several days.

Common symptoms to watch for during a relapse include:
• Numbness or tingling sensations
• Muscle spasms or stiffness
• Vision problems or partial vision loss
• Increased weakness
• Difficulty walking
• Problems with balance
• Cognitive issues (memory/thinking problems)
• Severe fatigue It's important to know that relapses can be different for everyone and may involve one or multiple symptoms at the same time. Some relapses develop slowly, making them harder to identify at first. If you experience any new or worsening symptoms that last more than 24 hours, contact your healthcare provider, as this could indicate a relapse requiring medical attention.

September 27, 2025

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