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New symptoms don't always mean new lesions. Some lesions can be "silent" initially but may cause noticeable symptoms if they worsen over time. Additionally, existing lesions can cause new or changing symptoms as they evolve, particularly in the case of "smoldering lesions" which can remain active and grow over many years Show Full Answer

New symptoms don't always mean new lesions. Some lesions can be "silent" initially but may cause noticeable symptoms if they worsen over time. Additionally, existing lesions can cause new or changing symptoms as they evolve, particularly in the case of "smoldering lesions" which can remain active and grow over many years. Yes, lesions appear as darker or lighter spots on MRI scans and can account for various symptoms. When contrast fluid called gadolinium is used during an MRI, it can show whether lesions are active (recent) or older. Active lesions appear brighter on contrast MRI, while lesions that don't light up are typically older than three months. The location of these lesions in the brain can determine what types of symptoms you experience.

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