Are there any new treatments for PPMS besides Ocrevus?
Currently, Ocrevus remains the only FDA-approved disease-modifying therapy specifically for primary progressive MS. However, there are some promising developments in research:
Potential treatments being studied
- Biotin (a vitamin) appears to act as a remyelinating Show Full Answer
Are there any new treatments for PPMS besides Ocrevus?
Currently, Ocrevus remains the only FDA-approved disease-modifying therapy specifically for primary progressive MS. However, there are some promising developments in research:
Potential treatments being studied:
- Biotin (a vitamin) appears to act as a remyelinating agent, helping to rebuild the protective myelin covering that MS destroys
- EBV-specific T-cell therapy showed clinical improvements in a small phase 1 trial and was well-tolerated by participants
- Remyelinating drugs are in development, though they may still be a few years away from availability
While these options show promise, they require further research before becoming widely available. In the meantime, your neurologist may be able to help manage specific PPMS symptoms through other medications targeting pain, fatigue, bladder control, or mood issues.
Physical therapy, occupational therapy, and lifestyle modifications like regular exercise and a healthy diet can also help improve outcomes and quality of life with PPMS.
It's worth having a conversation with your doctor about why Ocrevus isn't an option for you and what alternative approaches might work best for your specific situation.
November 5, 2025
Join
Your Privacy Choices
