Connect with others who understand.

  • Learn from expert-reviewed resources
  • Real advice from people who’ve been there
  • People who understand what you’re going through
Sign Up Log In
Powered By
Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyMSTeam Member asked a question 💭
Mims, FL

Looking for people who are taking Mavenclad. This is the medication my neurologist wants to try for me. I used to be on Ocrevus but I ended up getting breast cancer so I can’t take that medication anymore. I’m just looking for people who are on Mavenclad and how it’s working for you. I’ve been diagnosed with SPMS since 2015.. I was originally diagnosed with RRMS in 2009

November 20, 2025
 · 
Reactions
A MyMSTeam Member

Yes, I've been on it for 3 years. I have been on numerous MS medications, but none of them worked. I would go to my 6 month folkow up and have a new lesion. So, my neurologist said I had aggressive MS and put me on Mavenclad. I have not had 1 new lesion since I've been on it.

January 6
MyMSTeam

How is Mavenclad working for people with SPMS?

Mavenclad (cladribine) is an FDA-approved medication for treating secondary progressive MS, along with RRMS and CIS. It works by interfering with DNA processes in certain immune cells to prevent them from replicating, which helps control the inflammation that damages nerve Show Full Answer

How is Mavenclad working for people with SPMS?

Mavenclad (cladribine) is an FDA-approved medication for treating secondary progressive MS, along with RRMS and CIS. It works by interfering with DNA processes in certain immune cells to prevent them from replicating, which helps control the inflammation that damages nerve fibers in MS.

Mavenclad belongs to a class of medications called purine antimetabolites. By reducing specific immune cells, it helps manage the disease progression that comes with SPMS.

Since you've transitioned from RRMS (diagnosed in 2009) to SPMS (since 2015) and can no longer take Ocrevus due to breast cancer, Mavenclad represents a different treatment approach that your neurologist believes may be appropriate for your situation.

While I can provide information about how Mavenclad works, connecting with other MyMSTeam members who are taking this medication will give you real-world experiences. You can post on your Activities page to start conversations with others who have taken Mavenclad and learn about their experiences with the medication.

Have you discussed with your neurologist what to expect in terms of monitoring and potential side effects specific to your health history?

November 20, 2025
A MyMSTeam Member

Sorry, no I haven't tried Mavenclad. I have SPMS. Hope you do well on it!

January 8 (edited)
A MyMSTeam Member

Yah I finished it over 5 years ago. Go on the mavenclad Facebook group

November 21, 2025