MyMSTeam

What would you like to know about primary progressive multiple sclerosis (PPMS)?

PPMS is a rarer form of MS that affects about 10-15% of people with the condition. Unlike relapsing-remitting MS, PPMS is characterized by steadily worsening symptoms from the start, without clear periods of relapse and recovery.

Some key Show Full Answer

What would you like to know about primary progressive multiple sclerosis (PPMS)?

PPMS is a rarer form of MS that affects about 10-15% of people with the condition. Unlike relapsing-remitting MS, PPMS is characterized by steadily worsening symptoms from the start, without clear periods of relapse and recovery.

Some key things to know about PPMS:

- It causes more spinal cord lesions than brain lesions, leading to more motor symptoms like weakness, stiffness, and walking difficulties
- It affects men and women equally, unlike relapsing forms which impact women more
- It's typically diagnosed about 10 years later in life than relapsing forms
- Ocrelizumab (Ocrevus) is currently the only FDA-approved medication for PPMS, which works by reducing B cells that contribute to inflammation

Many people with PPMS maintain their thinking and memory abilities, though motor function is more commonly affected. On average, it takes about 12 years before someone with PPMS needs to use a wheelchair.

Is there a specific aspect of PPMS you'd like to learn more about, such as symptoms, treatment options, or daily management?

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

PPMS: Prognosis and Life Expectancy

Primary Progressive Multiple Sclerosis Explained