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A MyMSTeam Member asked a question 💭
Chicago, IL
December 16, 2025
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MyMSTeam

Why does your body itch sometimes?

Itching with MS is a type of nerve pain called cutaneous dysesthesia. It happens because MS damages the protective coating (myelin) around your nerves. When nerves can't send signals properly to your brain, the brain misinterprets these confused signals and assigns a familiar sensation to Show Full Answer

Why does your body itch sometimes?

Itching with MS is a type of nerve pain called cutaneous dysesthesia. It happens because MS damages the protective coating (myelin) around your nerves. When nerves can't send signals properly to your brain, the brain misinterprets these confused signals and assigns a familiar sensation to them—like itching.

This itching isn't caused by skin problems like allergies or rashes. It's your brain trying to make sense of faulty nerve signals caused by demyelination.

Where does MS itching typically occur?

MS-related itching can happen anywhere on your body, but commonly affects:
- Face and scalp
- Upper body and torso
- Arms and legs
- Sometimes just one side of the body

A MyMSTeam member described it as feeling "itchy, like there are bugs all over me." Another shared, "My head is always itchy."

Can MS medications cause itching?

Yes, some MS treatments can cause itching as a side effect. For example, alemtuzumab (Lemtrada) lists itching as a common side effect. Some members also notice their skin dries out from medications, making itching worse.

The good news is that MS-related itching usually isn't associated with a relapse—it can happen whether or not you're experiencing other MS symptoms. Talk with your neurologist about solutions if itching becomes bothersome.

December 16, 2025
A MyMSTeam Member

I saw my primary care dr. about that once. He told me to cut out caffeine. I told him that wasn't happening. He also told me to use unscented lotion or skin cream. That I did. My daughter works at a Walgreens and she brought me their version of Cetophil. I'm not sure if the itching just ran it's course or the moisturizer cream worked but the itching stopped. I do still itch occasionally but nothing like I did

December 17, 2025
A MyMSTeam Member

Yes usually as I’m trying to sleep or just drifting off to sleep. It is crazy sometimes.

December 16, 2025
A MyMSTeam Member

@A MyMSTeam Member I do know that Cetaphil is what my dermatologist recommends because it's the best on the market for dry skin. Although if you have extremely dry and cracking areas on the bottom of your feet or anywhere else I highly recommend Amlactin lotion. It's a little expensive but so totally worth it. I put it on my feet and wear socks over them at night and it clears it all up within days. (And I dislike wearing socks to bed, feet get hot but still worth it)

December 17, 2025
A MyMSTeam Member

I thought it was my soap. Shows how much I know ..

December 16, 2025

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